Systematic reviews require stringent research studies that are appropriately evaluated, and the goal is that all these pieces of evidence can answer a particular research query (Brown University Library, n.d.). These studies need to be distinctly defined, have a critical inspection, contain data, and results that have been analyzed and scrutinized (Brown University Library, n.d.). There are several main principles that back up the systematic review of the literature and they include equality, accessibility, coverage, focus, clarity, integration and transparency (Pittway, 2008, as cited by Charles Sturt University, n.d.). To perform a systematic review of evidence on this subject of the IV catheter insertion technique and orientation program currently used in the facility with the new registered nurses, its efficacy, and other methods, I will collect several evidence-based pieces of literature that have known to work and compare what methods have been known the be effective. Once I do that, I will gather further pieces of kinds of literature putting the focus on the method that I have chosen to be the safest and most effective way to insert an IV catheter and then critically appraise the investigations such as reviewing their methodologies, study framework, who the authors are, focus on results and try to avoid bias through understanding the limitations. I would also assess the level of evidence for each piece of literature. Once this part is done, it will be vital to have a practice guideline made. Clinical guidelines are recommendations on how to handle a diagnosis as well as other treatment methods (InformedHealth.org, 2006). Creating a clinical practice guideline (CPG) is not an easy task (Kredo et al., 2016). With that said, huge institutions generally have committees that perform these tasks. Guidelines are up-to-date knowledge therefore evidence that has been gathered must stay within a recent couple of years (InformedHealth.org, 2006). Educating the staff RNs about the investigations found and why they are essential is crucial and to design a clinical guideline, to do so, I need to have the practice setting handled, practice problem identification, gather current guidelines at the hospital in terms of IV insertion, look for kinds of literature that are strong such as randomized controlled trials, for example, call the manager/person in charge in terms of proposing a new innovation, present to the staff on why this new innovation must be given a chance, set up implementation date once its approved, disseminate results and then reevaluate on what can be improved and when the board of directors is in agreement and the new guideline looks polished, have it be submitted for approval (Rosenfeld, & Schiffman, (2009).